Monograph
D07AD01 - Clobetasol |
Not porphyrinogenic |
NP |
Rationale
Several references stating non porphyrinogenicity of glucocorticoids.
Chemical description
Extra strong glucocorticoid salve 0.005% and creme 0,05% used in dermatology. Risk for systemic exposure in application on large areas of the skin. Glucocorticoid: South African list: use Kalman, Bonkovsky: believed to be safe The Merck Manual: use Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939.: safe
IPNet drug reports
Uneventful use reported in 4 patientS with acute porphyria.
Similar drugs
References
Tradenames
Clarelux · Clobetasol · Clobetasolpropionaat · Clobetasolpropionaat EU · Clobex · Dermovate · Eczoria 
Cabesol · Clarelux · Clobex · Dermovate 
Clarelux · Clobex · Clobisdin · Clovate · Decloban 
Clobex · Closanasol · Dermovate · Infilea 
Clobecare · Clobesol · Clobetasolo · Etrivex · Olux · Sublasol 
Clobetasol · Clobetazol · Dermovate · Infilea 
Clarelux · Clobetasol · Clobex · Dermovate 
Clarelux · ClobaDerm · Clobetasol · Clobetasol 0.05% cream 10% in Aqueous cream · Clobetasol 0.05% cream 10% in Unguentum M cream · Clobetasol 0.05% cream 25% / Propylene glycol 40% in Aqueous cream · Clobetasol 0.05% cream 25% / Propylene glycol 40% in Unguentum M cream · Clobetasol 0.05% cream 25% in Cetomacrogol cream (Formula A) · Clobetasol 0.05% cream 25% in White soft paraffin · Clobetasol 0.05% cream 30% in Aqueous cream · Clobetasol 0.05% cream 50% in Unguentum M cream · Clobetasol 0.05% cream 50% in White soft paraffin · Clobetasol 0.05% ointment 10% in Unguentum M cream · Clobetasol 0.05% ointment 10% in White soft paraffin · Clobetasol 0.05% ointment 20% in Cetomacrogol cream (Formula A) · Clobetasol 0.05% ointment 20% in White soft paraffin · Clobetasol 0.05% ointment 25% / Coal tar solution 5% / Salicylic acid 2% in Yellow soft paraffin · Clobetasol 0.05% ointment 25% / Coal tar solution 5% in White soft paraffin · Clobetasol 0.05% ointment 25% / Coal tar solution 6% in Unguentum M cream · Clobetasol 0.05% ointment 25% / Dithranol 0.05% in White soft paraffin · Clobetasol 0.05% ointment 25% in Unguentum M cream · Clobetasol 0.05% ointment 25% in White soft paraffin · Clobetasol 0.05% ointment 30% in White soft paraffin · Clobetasol 0.05% ointment 50% / Propylene glycol 48% / Salicylic acid 2% ointment · Clobetasol 0.05% ointment 50% in Carmellose gelatin paste · Clobetasol 0.05% ointment 50% in Emulsifying ointment · Clobetasol 0.05% ointment 50% in White soft paraffin · Coal tar / Clobetasol · Dermovate · Etrivex 
Clobetasolpropionat · Clobex · Closol · Dermovat · Infilea 
Clobex · Dermovat · Dermovate 
Clarelux · Clobederm · Clobetasol · Clobetaxon · Clobex · Dermovate · Infilea · Novate 
Cabesol · Clarelux · Clobex · Dermovate 
Clobex · Dermovat 
Clobex · Dermovat 
Clobagel · Closanasol · Dermovate 
Dermovate 
Dermovate 
Klobetazol 
Clarelux · Clobaderm · Clobetasol · Clobex · Cormax · Dermovate · Dermovate nn · Embeline · Embeline e · Etrivex · Impeklo · Impoyz · Olux · Olux e · Temovate · Temovate e 
Clobetasol