Monograph
H02AB01 - Betamethasone |
Propably not porphyrinogenic |
PNP |
Rationale
Glucocorticoid. Several references consider it safe.
Chemical description
Glucocorticoid used in treatment of staus asthmaticus, severe allergic conditions, anaphylaxis, etc. Mineralocorticoids: South African list: use. French list: authorized. Kalman, Bonkowsky: probably safe Michael Moores list: safe. The Merck Manual: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncans Diseases of Metabolism, Philadelphia, WB Saunders. 1980,p 939: safe. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997:safe
Therapeutic characteristics
Hepatic exposure
Metabolism and pharmacokinetics
Preclinical data
Personal communication
Published experience
IPNet drug reports
Uneventful use reported in 7 patients with acute porphyria.
Similar drugs
References
Tradenames
Celestone 
Celestone · Diprophos 
Betametasona · Celestone Cronodose 
Diprophos 
Albaflo · Bentelan · Betametasone · Etason · Ibet 
Diprophos 
Betnesol · Diprophos 
Betamethasone · Betnelan · Betnesol 
Diprofos · Diprophos · Diprospan 
Bentelan · Betametasone · Betamethasone · Betapred · Celestan · Celeston 
Celestone · Diprophos 
Celestone · Diprophos 
Diprospan 
Betapred · Celeston 
Diprophos 
Celestone Chronodase · Flosteron · Kuterid