Monograph
M01AX05 - Glucosamine |
Not porphyrinogenic |
NP |
Rationale
No CYP-dependent metabolism.
Chemical description
Relatively small and water-soluble molecule (MW 179)
Therapeutic characteristics
Endogenous substance that possibly works by a positiv influence on cartilage metabolism. Common adverse reactions that can be mistaken for porphyria symptoms are dyspepsia, stomach ache, diarrhoea, constipation, nausea.
Hepatic exposure
Significant
Metabolism and pharmacokinetics
Metabolized mainly by the hexosamine-system and thereby independent of the cytopchrome P-450 system (1).
Preclinical data
None
Personal communication
None
Published experience
None
IPNet drug reports
Uneventful use reported in 28 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PMID |
|---|---|---|
| * | Summary of Product Characteristics | |
| 1. | 1) SPC glucosamine (updated: 2007-12-20).
|
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Tradenames
Dolenio · Glucosamine 
Dolenio · Donacom · Glucosamine 
Acenam · Arafisio · Cartisorb · Coderol · Duartron · Glucosamina · Glufan · Gluniro · Xicil 
Arthryl · Atrofort · Cartilamin · Dolenio · Dona · Dona Arthro · Droglycan · Glukozamin · Movex · Tonicor 
Slideflex 
Alateris · Cozachew Fizz · Cozachew Meltdown 1500 · Cozatabs 750 XL · Dolenio · Fosachew · Fosaveg · GlucOsamax · Glucosamine · Glusartel · Gosa-S · Gosachew · Gosaveg · Joint-Flex · Joint-Flex 1000 · Joint-Flex Daily · Joint-Flex Max One A Day · Ostex · Pro Coxam · Seven Seas Jointcare Extra 
Dolenio · Glucofarm · Glucosamin · Revadol 
Donacom · Glucosamin · Samin 
Arthryl · Dolenio · Flexove 
Dolenio 
Dolenio · Glucomed 
Arthryl · Glucosamin 
Arthryl · Dolenio · Glucosamin · Glucosamina · Glucosamine · Glucosan · Gool · Probeven · Remaid 
Arthryl · Glucosamin · Glucosamine 
Arthryl · Dolenio · Glucadol · Glucosamin · Glucosamine · Prubeven 
Dona · Metaspon 
Bonartos · Dona · Fidiflex · Flexodon · Glukozamin · Voltaflex Glukozamin 
NSAIDs 
Glucosamina 
Glucosamine