Monograph
N01AH01 - Fentanyl |
Propably not porphyrinogenic |
PNP |
Rationale
Substrate to, and inhibitor of CYP 3A4. Administered in ug dose. Several references consider it safe for use.
Chemical description
Opioid analgesic used (509-100 ug / dose) intravenously in general anesthesia during long and moderatly long surgery. Used together with droperidol in neuroleptanalgesia typ II. Probably metabolized by CYP3A4. MFM James, RJ Hift. Porphyrias. Br J Anaesth 2000; 85, 143-53: use EPI-list: safe. Australian list: safe. South African list: use. French list: use. Austarlian list: safe.
IPNet drug reports
Uneventful use reported in 5 patients with acute porphyria.
Similar drugs
References
Tradenames
Fentanyl 
Fentanyl 
Fentanest · Fentanilo 
Fentanyl 
Fentanil · Fentanyl 
Fentanyl 
Fentanyl · Sublimaze 
Fentanyl · Haldid 
Fentanyl 
Fentanyl 
Fentanyl 
Leptanal 
Fentanyl · Fentanyyli 
Fentanyl 
Fentanyl 
Fentanyl 
Fentanil · Fentanyl 
Fentanil · Fentanyl