Monograph
N07BC01 - Buprenorphine |
Not porphyrinogenic |
NP |
Rationale
Opioid, substrate of CYP 3A4. Clinical experience (Sweden) of non-porphyrinogenicity. Four references consider it safe.
Chemical description
Partial opioid agonist/antagonist used in treatment of opioid dependence, metabolized by CYP 3A4 and glucuronidation. Inhibitor of CYP 3A4 and 2D6. Australian list: safe EPI-list: safe South African list: use French list: use
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
Tradenames
Buprenorfine · Buvidal · Sixmo 
Buprenorphine · Buvidal · Sixmo · Subutex 
Buvidal · Sixmo 
Buprenorfin · Buvidal · Sixmo 
Buprenorphin · Buvidal · Subutex 
Buprenorphine · Espranor · Gabup · Natzon · Prefibin · Sixmo · Subutex 
Buprenorphin · Buprenorphine · Buvidal · Sixmo · Subutex 
Buprenorphine · Buvidal · Espranor · Sixmo · Subutex 
Buprenorphine · Buvidal · Sixmo 
Buvidal · Subutex 
Buprenorphine · Buvidal · Sixmo · Subutex 
Buvidal · Sixmo · Subutex 
Buprenorfina · Buprenorphine · Busette · Buvidal · Sixmo · Subutex · Transtec 
Buprenorphine · Buvidal · Sixmo · Subutex 
Buprenorphine · Buvidal · Sixmo 
Buprefex · Buprenorfin · Buprenorphine · Buprobol · Buvidal 
Addnok · Buprenorfin · Buvidal · Subutex 
Buvidal · Sixmo