Monograph
V08CA09 - Gadobutrol |
Not porphyrinogenic |
NP |
Rationale
Gadobutrol is not metabolised. It is excreted unchanged through the kidneys.
Chemical description
Gadobutrol is a nonionic gadolinium chelate.
Therapeutic characteristics
Gadobutrol is used as a magnetic resonance contrast medium. It is administered intravenously.
Hepatic exposure
Not significant.
Metabolism and pharmacokinetics
Gadobutrol is not metabolised and more than 90% of a dose is excreted in the urine within 12 hours.
Similar drugs
References
| # | Citation details | PMID |
|---|---|---|
| * | Drug reference publications | |
| 1. | Sweetman SC, editor. Martindale: The complete drug reference. Gadobutrol. Pharmaceutical Press 2009.
|
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| * | Summary of Product Characteristics | |
| 2. | Norwegian medicines agency. Summary of Product Characteristics (SPC). Gadovist.
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Tradenames
Gadovist 
Gadovist 
Gadograf · Gadovist · Pixxoscan 
Gadovist 
Gadovist 
Gadograf · Gadovist 
Gadobutrol · Gadovist 
Gadovist 
Gadovist · Pixxoscan 
Gadovist · ProHance 
Gadovist 
Gadovist 
Gadovist 
Gadovist · Kiralda 
Gadovist 
Gadograf · Gadovist 
Gadobutrol · Gadovist 
Gadovist · Memovist 
Gadavist 
Gadobutrol